Here is a list of major Intel native applications for Mac OS X: (Click on the application to go to their website)

Apple:

Mac OS 10.7.1 (all internal apps too)
Mac OS 10.6.2 (all internal apps too)
Mac OS 10.5.8 (all internal apps too)
Mac OS 10.4.11 (all internal apps too)
Mac OS 10.7.1 Server Edition
Mac OS 10.6.2 Server Edition
Mac OS 10.5.8 Server Edition
iLife '06/'08/‘09/’11
iWork '06/'08/‘09
iTunes 10
MobileMe
QuickTime
Final Cut Studio
Aperture 1.5/2.0
Apple Remote Desktop
Final Cut Express HD

Productivity/Graphics:

Microsoft Office 2008/2011
Mathmatica
Adobe Creative Suite 5.5
FileMaker Pro 11
Bento 4
QuarkXpress 9
Print Explosion Deluxe 3
Cinema 4D

Educational/Research:

Sesame Street® First
Sesame Street® Lean Play & Grow
Arthur’s 1st Grade Learning System
Mavis Beacon Teaches Typing Deluxe
ReaderRabbit
Reunion 9
RosettaStone

Browsers/Internet:

Safari
Chrome
FireFox
Acquisition
Transmission
Transmit
Camino

Utilities:

Flip4Mac
Parallels
VMware
Stuffit Expander 2009 (email address required for download for free version)
ESET NOD32
Intego Virus Barrier X6
Norton Confidential 1.0
Norton AntiVirus 10
McAfee Virus Scan
TechTool Pro 5
DiskWarrior 4

Financial:

Quicken Essentials for Mac
QuickBooks Pro 2009
MYOB Account Edge

Media:

Mac Speech Dictate
EyeTV
VLC
Toast 11 Titanium
Popcorn 4

Games:

RollerCoaster Tycoon 3
Doom 3
Sims 2
SpiderMan 2
BattleField 1942
Halo
Quake II-Quake 4
Age of Empires III
Bugdom 2
Call of Duty 2
Call of Duty 4
Command & Conquerer Generals
Nanosaur 2
Zoo Tycoon
SecondLife
World of Warcraft
Madden NFL 2008
Tiger Woods PGA 2008
Battlefield 2142
Command & Conquer 3
Need for Speed
Harry Potter and the order of Phoenix
Sid Meiers Civilization IV
Stubbs the Zombie
Guitar Hero: Aerosmith Edition

Note: Not all applications and games are shown here. For a complete list, visit the Mac App Store.